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The latter analysis included a graphic assessment of the changing relative risk over time for women vs men. However, stratified analyses demonstrated that sex differences in risk occurred only early after catheterization and were most apparent among patients undergoing revascularization. The early risk-adjusted relative risks for women vs men were elevated at 3. This finding may at least partially explain the discrepancies in results from earlier studies on sex differences in outcomes of cardiac care. Sex differences in cardiac care and outcomes have been widely investigated since Steingart et al 1 stimulated clinicians to consider sex-based biases in care practices.

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PCI in women: is sex still an issue?

Long-Term Outcomes in Women and Men Following PCI | PracticeUpdate

Advances in percutaneous coronary intervention PCI , including the introduction of drug-eluting stents DES , have dramatically improved long-term prognosis in patients with obstructive coronary artery disease. Nevertheless, prior studies examining sex-related outcomes following PCI have yielded conflicting results, likely due to small sample sizes, lack of randomization, short duration of follow-up, and use of outdated technologies. In the present large-scale, pooled analysis of individual patient data from contemporary randomized PCI trials, the authors aimed to address this knowledge gap by examining the effect of sex on 5-year cardiovascular outcomes following PCI. Among 32, patients,

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Association of Sex With Outcomes in PCI Patients

Women are more likely to suffer from a cardiogenic shock CS as the most severe complication of an acute myocardial infarction AMI and tend to have a higher mortality. Data concerning optimal management among women with CS are lacking. Aim of this study was therefore to better define characteristics of women suffering a CS and to investigate the influence of sex on different coronary revascularisation strategies. Primary end-point was a composite of death from any cause or severe renal failure leading to renal-replacement within 30 days after randomisation. We investigated sex-specific differences in general and according to the revascularisation strategies.

The data are overwhelming and not uncommonly, the results are often discrepant. So, what do we know about CAD in women? We know that there are clear differences by sex in the presentation of patients with CAD. Yet, many of the differences in outcomes have been attributed to sex differences in the presentation and treatment of these patients.